Everything you need to know about the fertility drug letrozole
Trying to get pregnant" If you?re having trouble, your doctor may prescribe a drug called letrozole. Sold under the brand name Femara, letrozole was originally created to treat breast cancer, but doctors found it also induces ovulation, so since 2000, it has been used off-label to help women with fertility issues.
The drug is used as a first-line treatment for people who have polycystic ovary syndrome (PCOS), where you either don?t ovulate at all or do so irregularly, and most other ovulatory disorders, says Cliff Librach, a reproductive endocrinology and fertility specialist, director of the CReATe Fertility Centre in Toronto, and president-elect of the Canadian Fertility and Andrology Society. It can also be used to treat unexplained infertility. How does letrozole work"
Letrozole is typically taken once a day for five days. When you take it, it stops androgens in your body from converting into estrogen. When the estrogen is blocked, the pituitary gland gets a message that it needs to produce follicle stimulating hormone (FSH), which stimulates the ovary to produce an egg. And some women on letrozole actually release more than one egg because they product more FSH while on letrozole than a woman produces when ovulating naturally.Â
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